[Zope] Periodic Proxy Error: Connection Refused

[Adam Kessel]

I'm running apache 1.3 and Zope out of Debian unstable.  Zope 2.6.4-1.1,
Apache 1.3.29.0.2-4.

Every day or two, I notice my Zope site is slowing down, and eventually I
get a Proxy error: connection refused when trying to access my Zope site.  

Shutting Zope down and restarting it seems to fix the problem for another
day or so.

I've also, in the past, had trouble with what appears to be an Apache
memory leak, but I never was able to diagnose it nor was anyone else[0].  

I'm using a fairly vanilla configuration for Apache/Zope, including
VirtualHostBase.  The relevant .htaccess line:

RewriteRule ^zope/*(.*) http://my-domain.com:9673/VirtualHostBase/http/my-domain.com:80/zope/$1 [P]

(not the real strings, but otherwise accurate)

Can anyone give me some tips on troubleshooting/fixing this?  I'm not
seeing anything more in the error logs but:

[Mon Apr 12 10:28:30 2004] [error] [client [IP address]] (111)Connection refused: proxy connect to [IP address] port 9673 failed 
-- 
Adam Kessel
http://adam.rosi-kessel.org

[0] http://lists.debian.org/debian-apache/2003/debian-apache-200309/msg00065.html