[Zope-dev] When should one call Connection.sync?

I am using ZODB 3.2 in a twisted based web application. I have read that I need to call sync to keep the connection up to date. When exactly should I call sync? Are there any drawbacks with calling it immediately after getting a connection, like this: # for each http request. connection = db.open() # (a DB instance) connection.setLocalTransaction() connection.sync() # start using the ZODB here. # if something needs to be committed connection.getTransaction().commit()