[Zope] How to talk to ZODB?

Hallo, I wanted to put some management of my CMF site to an external application. What is the most convinient way to access persistent objects and modify them? Should I integrate ZODB with my application or use any protocol to communicate (WebDAV, XML-RPC)? I suppose that the second way is better. Is there any howto? Maybe I should ask google, but about what? I think of using libxmlrpc with wxPython (thank you Phill), but maybe there are any other suggestions. Are there any out-of-the-box solutions? Pawel Lewicki