[Zope] I have tried everything!!! Isn't it possible to host several domains in 1 Zope and have apache running ????

Hello, Maybe I am stupid but really .. Every site I have visited that runs Zope doesn't have the ugly :8080 present in the URL. Have do you do it ???? And how do I host several domains in one Zope ??? I have read - and tried - almost every howto on Zope.org but they are very confusing. On thing I have descovered is that SiteRoot is a "mean" product - or I just don't know how to use it. Please .. help ... Gitte