I had this problem...and the paths reported are a bit spurious if I remember rightly. I think I got complaints about Tk/Tcl, then MTS, then something else. The dialog that popped up is on a remote server, so I had to fix this quickly. To fix it. I reinstalled python (Don't know if I needed to do this) and Tcl/TK (part of the same installer). I don't think you need to do this. Then I copied and pasted the PyWinTypes.dll. Tk80.dll. (Maybe the Msvcrt.dll too) into to the Zope/lib/Python/ folder. If they're already there, copy them into your python DLL folder. OK, I admit it, I sprayed them all over the place, restarted and I've not had any bother since. This problem *may* be caused by the Tcl install, making a mess of the registry. I don't think you need Tcl for zope, so next time I won't install it and see if the same problem happens hope this helps tom