[Zope] ZoDB and BIG FILES

Hi there, I am about to finalize a Zope 2 site. It will mainly play the role of groupware app and storage server. My question is : i know i ll get quicly a big amount of PSD files (photoshop) they are usually quite heavy. Do you rekon i should store them on my server file system rather than the ZODB ? Do you see any trouble putting them all into the DB in a longer term ? (i know my python is large-file compiled). Storing on both FS and ZODB is it an easy thing to do ? Thanks in advance Seb