[Zope] Set cache association on creation

I am using Zope 2.6.2. I would like to automatically set the cache association of files in a folder on creation(the files are created by Zipfolder so I don't have direct control of creation process). Is there some mechanism to do this? Failing that can somebody provide some information/guidance on setting associations in a Python script either in bulk or by individual file after creation. Brian Sullivan Courses by Wire (www.coursesbywire.com)