I tried all what's currently available except to dig into Zope's win32 services machinery: I did install it manually after removing the extra underscore in "INSTANCE__HOME". I added a PYTHONPATH system variable for both the path of the alternate Python installation and the Zope software; and also I changed the PYTHONW variable within zopeservices.py to the executable of this other Python installation (which I need due to I have installed there win32all), but the service refuses to start. The event log just tells : Zope_307702503 (Zope instance at G:\Zope-Instance): process died unexpectedly. Will attempt restart after 160 seconds. If I run it manually everything is fine. Has anyone else had this same problem? Guess I ran out of stamina at this very moment ;) Ausum