[Zope] Problem with Zodb connections pool

Hi all, I've a system with Zope 2.8.8 that since some weeks is very slow. The python process keeps busy the CPU (98-99%) and the memory used by the process is growing up. Every day a script makes a pack of the ZODB and restarts Zope so the Data.fs size is stable (about 350MB). In the event.log I can see many of this warnings: 2009-10-14T11:59:14 WARNING ZODB.DB DB.open() has 8 open connections with a pool_size of 7 What does it mean? I can see also some of these messages: 2009-10-14T12:14:16 INFO ZODB.Conflict database conflict error... According to you, are the two messages related? Thank you very much claudio