[Zope] Hotfix_2001-09-28... applied and now client connections refuse

I set up a new 2.4.1 install on a SuSe 7.2 distrubution, changed file permissions as per an informative install article on the zope site, tested it and it worked fine (via localhost and remote connection) Then I installed the 2001-09-28 hotfix. able to start up ok, and the ./start script showed the hotfix was applied, but now I get 'connection refused when attempting....' error (localhost or remote) when I try to connect. Any ideas ?? rich pinder