Hi Tom, any hint on Your Zope version could possibly intesting when mailing tracebacks ;-> (I actually started considering NFS issues first before looking at the filenames in the traceback ...)

My site works fine when served by Zope (http://www.aim23.com:8080/)

But I don't understand the error when I try to access through pcgi on NT4 (http://www.aim23.com/aim.cms)

(<class ZODB.POSException.StorageSystemError at 0061996C>, 'Could not lock the database file. There must be\nanother process that has opened the file.\n<p>')

This is a hard boiled error message You get any time the method failed, for what reason whatever. Maybe You could patch the code temporarily in C:\PROGRA~1\Zope\lib\python\ZODB\lock_file.py from try: LockFile(un,0,0,1,0) # just lock the first byte, who cares except: raise error, ( "Could not lock the database file. There must be\n" "another process that has opened the file.\n" "<p>") to simply: LockFile(un,0,0,1,0 and look at the underlying error message. Either You lack permission to lock, or You have started two Zopes accidentially, one on port 8080 and a different for pcgi ? (Just a thought.) Cheers, Clemens